Paul Ryan is taking on the Obama campaign directly over Vice President Biden’s “back in chains” comment, calling them the mark of a “desperate” campaign as President Obama defends his running mate against bipartisan criticism.

In an interview with Sean Hannity on Fox News Radio, Ryan kept up the new tough tone that Mitt Romney set earlier in the week.

“You know, these are the kinds of things you say when you’re desperate in a campaign,” Ryan said of Biden’s comments. “I think you’re going to hear more of these things as we go on because they have a terrible record and can’t run on it so they’re going to kind of sink this campaign to these low levels to distract people.

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